Estill CF, Spencer AB
From a neurobiological standpoint, the development and intensification of migraine into a debilitating condition involve intricate interactions between neurons, glial cells, vascular components, and inflammatory mediators within the TVS (6, 912)
Klicek, R., et al., Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability
Sattar N, Neeland IJ, Dahlqvist Leinhard O, Fernndez Land L, Bray R, Linge J, et al
It is classified under the GLP-1 (glucagon-like peptide-1) drugs as it controls blood sugar levels as well as aid in weight loss
Reflecting on the clinical implications, St-Pierre says that the findings support cautious use of GLP-1 RAs in selected patients with IBD when prescribed for approved metabolic indications, with appropriate counselling and monitoring. At the same time, she noted that the findings highlight substantial evidence gaps and believes future research should move beyond proxy outcomes and incorporate prospective, IBD-specific designs that integrate objective inflammatory measures with robust metabolic phenotyping. Moreover, there should be special considerations on the effects of GLP-1 RAs on body composition of patients with IBD, she adds
