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Obes Sci Pr

Via the vagus nerve, gastrointestinal GLP-1 production stimulates the Arc and PVN in the hypothalamus as well as the NTS and area postrema, a locus of central nausea

The hazard-ratios [95% CI] of the composite kidney outcome with GLP-1 RAs versus basal insulin were 0.96 [0.821.11] (p = 0.566) and 0.71 [0.540.95] (p = 0.020) in the ITT and AT analyses, respectively

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An oral version of these drugswhich are known as glucagon-like peptide 1 (GLP-1) receptor agonistscould be more accessible and would come without the inconvenience, pain or medical waste of shots