But others report improved mood as appetite stabilises and weight decreasesPMC, 2023
Additionally, pharmacokinetic differences were predicted in subjects based on factors such as age, body weight, sex, race, ethnicity, and injection site, with most GLP-1 RAs and a dual GLP-1/GIP RA exhibiting only minor variations
Mood stabilising drugs increase CaMKK2 activity and abundance Mood stabilisers are a class of drugs that are used to treat and manage both the manic and depressive phases of bipolar disorder [159]
Impact of treatment with GLP-1RAs on suicide attempts in adults persons with type 2 diabetes: A retrospective comparative effectiveness study based on a global TriNetX health research database
Nature 458, 10561060
It was also shown to reduce adipose tissue mass in vivo through activation of adipose triglyceride lipase and lowering the expression of fatty acid synthase [97]