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The effect of copper on the GM has also been demonstrated in Nile tilapia, where exposure to subacute levels (0,5 mg/L, 1 mg/L and 2 mg/L Cu 2+ ) for 14 days resulted in reduced bacterial diversity, a decreased abundance of Ruminococcus and Shigella and increased abundance of Edwardsiella and Aquabacterium (Zhang et al., 2022a)

Variants in the CTLA4 gene may impair this inhibitory function, allowing autoreactive T cells to proliferate and attack the thyroid

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Patients often undergo multiple sessions during the initial phase of treatment, which may influence the total cost

USA 109 , 1753717542 (2012)