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Phattarataratip, E., Olson, B., Broffitt, B., Qian, F., Brogden, K.A., Drake, D.R., et al., Mol

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These brain functional studies clearly indicate that disruption of hypothalamic control of satiety, dysfunction in the associated reward circuitry regions and impairment in inhibitory control areas jointly contribute to extreme hyperphagia and obesity in PWS

Alcohol inflames liver tissue and disrupts its normal filtering function