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Funding: Research reported in this publication was supported by the National Center For Advancing Translational Sciences of the National Institutes of Health under Award Number KL2TR001856 and the National Institute of Diabetes and Digestive and Kidney Diseases (Luo) under Award Number K23DK120956

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Together these data support a stronger brain dependence of the body-weight-lowering effects of GLP-1MK-801 compared with semaglutide