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It works by helping your body release insulin after meals, slowing digestion to help you feel full longer, and signaling areas of the brain that control hunger and cravings

Similarly, Contrave leads to 5%6% reduction in weight vs 1% with placebo (Greenway FL et al, Lancet 2010;376(9741):595605)

Insurance coverage influences out-of-pocket expenses

A 2024 meta-analysis of 27 randomised controlled trials involving approximately 200,000 participants found that GLP-1 receptor agonists were associated with a 24% reduced risk of seizures and epilepsy compared to placebo

The plan is to supply different doses than the originators authorised products and to offer combinations of products intended to reduce side effects

What to Watch in the Second Half of 2026 With TRIUMPH-1, TRANSCEND-T2D-1, and the TRIUMPH-1 OSA substudy all now confirmed, the remaining milestones in 2026 are TRIUMPH-2 and TRIUMPH-3 and the NDA submission that follows them