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Additionally, as detected with a Seahorse XF analyzer, we found that the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) were both decreased in ACTL6A-KD cells (Supplementary Fig 2d, e)

Vitamin C plays a key role in immune function, collagen production, and protection against oxidative stress

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Research demonstrates that NNMT expression increases significantly with advancing age, particularly in metabolic tissues, contributing to the progressive decline in NAD+ levels observed during aging

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Li S.Y., Zhang T.J., Wu Q.X., Olounfeh K