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The largest study to date assessed the use of metformin 1 g, twice daily, in 428 people with type 1 diabetes who were treated for 3 years, with a primary endpoint of changes in mean carotid intimamedia thickness, a marker of cardiovascular disease risk

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The SELECT trial demonstrated that Wegovy 2.4 mg also reduces the risk of major adverse cardiovascular events in adults with established cardiovascular disease and obesity or overweight