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Many patients begin with 4-8 week initial cycles to establish baseline response and assess sleep quality improvements, with protocols often extending to 12+ weeks for comprehensive sleep pattern restoration

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Salvage SC, Chandrasekharan KH, Jeevaratnam K, Dulhunty AF, Thompson AJ, Jackson AP, Huang CL (2018) Multiple targets for flecainide action: implications for cardiac arrhythmogenesis