12 Earlier studies were directed at delabeling patients with greater need for sulfonamide antibiotics, such as trimethoprim-sulfamethoxazole for P jirovecii prophylaxis in immunosuppressed populations, including patients with cancer, human immunodeficiency virus, or acquired immunodeficiency syndrome in whom the benefit of DOC outweighed the risk
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The active fraction turned out to be a tripeptide glycine, histidine, lysine bound to a copper ion.1 That observation kicked off five decades of research
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