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The safest approach is to restart at the lowest dose and titrate up, though this may not be practical for frequent alternating

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25 per 10 000 person-years), corresponding to a 39% higher relative risk

Multi-strain probiotic complex complementary probiotic strains selected to work synergistically with Akkermansia, supporting the complete gut microbiome environment for digestive regularity, gut barrier function and microbial diversity

doi: 10.1038/ncomms10690 11 SharmaSLeeDLiBQuinlanMTakahashiFMaheswaranSet al