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Those who lose the most weight tend to regain the most, but they can often maintain some weight loss compared to where they started

People taking tirzepatide were more likely to lose at least 10 to 15% of their body weight compared with people taking semaglutide

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Figure 1 Statements Author contributions All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication

Modified DPP-4 can not only mask the enzymatic hydrolysis site of DPP-4 but also bind closely with albumin to reduce renal excretion and prolong the half-life

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