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However, during mitochondrial stress (physical, chemical, and biological) and damage, mtDNA could be abnormally released into the cytosol or extracellular space

HartmannA.AgurellE.BeeversC.Brendler-SchwaabS.BurlinsonB.2003Recommendations for conducting the in vivo alkaline Comet assay

Delaying the onset of neuromuscular fatigue during intense exercise [8]

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Prior to the synthesis and isolation of these peptides, research into accelerated tissue healing and recovery relied largely on broad growth factors and nonspecific interventions