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Three RCTs [13, 33, 34] involving 186 patients provided low certainty evidence (Table 2) that L-carnitine supplementation may induce or no difference in changes in the total cholesterol levels (MD: 11.80, 95%CI: 27.13 to 3.53)

Abbreviations: AMD, age-related macular degeneration

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Moreover, HGF overexpression attenuates monocyte chemoattractant protein-1 (MCP-1) induction, predominantly in astrocytes, thus reducing accumulation of activated microglia (Kadoyama et al., 2007)

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