Same thresholds as off-label Ozempic, but Wegovy is the approved indication
Many find 4mg or 8mg effective Consider microdosing if GI side effects are limiting your progress Use a calculator to visualize your protocol and track steady state References Jastreboff AM, Kaplan LM, Fras JP, et al
Semaglutide mimics glucagon-like peptide-1, a hormone the gut releases after eating
The National Institute for Health and Care Excellence (NICE) notes that the prevalence of Vitamin B12 deficiency is approximately 6% in those under 60 years old, rising to 20% in the over 60s
For active individuals, a dose closer to 1,000 mg to 2,000 mg might help maximize fat burning and improve performance
PMID: 41278761 Res Sq2025 May 25