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Eu J Pharmacol 2007

Consequently, the familys refusal to consent to additional invasive diagnostic procedures mandated a conservative management approach based on limited imaging data, highlighting the clinical challenge of balancing diagnostic uncertainty with patient preferences and therapeutic urgency

I suspect this is from the glucagon agonism of the drug as glucagon stimulates the formation of extra bile acids/bile salts in the liver which can be very irritating to the intestinal lining causing diarrhea