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Neuschwander-Tetri BA, Loomba R, Sanyal AJ, Lavine JE, Van Natta ML, Abdelmalek MF, Chalasani N, Dasarathy S, Diehl AM, Hameed B, Kowdley KV, McCullough A, Terrault N, Clark JM, Tonascia J, Brunt EM, Kleiner DE, Doo E (2015) Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

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It reduced neuronal damage and improved memory, locomotion, and coordination, possibly by influencing gene expression in hippocampal tissues

CB4211 Clinical Trial: The Only Human Data (CohBar 2021) CB4211, a MOTS-c analog developed by CohBar, completed Phase 1a/1b clinical trials

doi: 10.1016/j.freeradbiomed.2018.03.038

Duncan of Lowell Observatory reported seeing "a rectangular patch of light on the floor" through the slit of the dome housing 24-inch Clark telescope in November 1905