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The early phase begins within minutes of eating, when nutrients in the upper gastrointestinal tract trigger neural and hormonal signals that stimulate L-cells even before food reaches the distal intestine

This improved score persisted after a 12-week washout period as well

We want you to be successful without suffering

Because the drug doesn't address the underlying cause

These are signals, not conclusions but theyre coming directly from patients, unprompted, and thats worth paying attention to, says the first author, Neil Sehgal, a doctoral student at the University of Pennsylvania in Philadelphia

If a patient depends only on appetite suppression, maintenance may become difficult when appetite changes or medication access changes