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Growing Complexity in Site Operations Sites now manage an average of 22 distinct sponsor/CRO platforms per trial spending roughly 12 hours each week on redundant data entry according to ACRPs March 2025 survey

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Network-based bioinformatics, integrated with ML, has also eased the repurposing of drugs as well as the identification of synergistic combinations, based on the match between tumor molecular signatures and the pharmacogenomic data from GDSC and CCLE (254)

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