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Common Side Effects Nausea Diarrhea Vomiting Constipation Stomach pain Decreased appetite Headache Serious Side Effects (Rare) Pancreatitis Gallbladder complications Kidney injury, potentially linked to dehydration from nausea/vomiting Severe allergic reactions Vision alterations in type 2 diabetes patients Increased heart rate A boxed warning accompanies oral semaglutide regarding the risk of thyroid C-cell tumors based on animal testing

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Jan 2004;15(1):23-26

The yellow ovals in Panel B indicate enzymes whose activities differ between males and menstruating females

358 These lipid abnormalities contribute to the dyslipidemia pattern often observed in individuals with metabolic syndrome