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This can mean better control for metabolism for those with insulin sensitivity, including those with type 2 diabetes and those with PCOS

GLP-1 receptor agonists (semaglutide) and dual GLP-1/GIP receptor agonists (tirzepatide) do not directly cause muscle wasting

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What it is / mechanism Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that selectively agonizes the ghrelin receptor (GHS-R1a) on pituitary somatotrophs, triggering a signaling cascade that produces a pulsatile release of growth hormone, while also blunting somatostatin the body's natural GH-inhibiting signal