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higher than clinical doses) of rozanolixizumab in pregnant NHPs indicate that adverse fetal toxicity may occur independently of maternal toxicity [342]

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Correlation of vascular structural changes in a cadaveric model and obesity-related cardiovascular non-communicable diseases

For example, one study showed that in people with type 2 diabetes, treatment with semaglutide (1 mg weekly) causes an average loss of about 6% of body weight over 40 weeks, while treatment with tirzepatide (15 mg/week) leads to an 11% weight loss in this population