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Why is it important to start GLP-1 medications with a gradual dose increase, and how does this improve safety and effectiveness

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Eur J Clin Investig 27:533536 von Websky K, Reichetzeder C, Hocher B (2014) Physiology and pathophysiology of incretins in the kidney

Some clinical guidelines recommend metformin as a first-line treatment for type 2 diabetes