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The mechanisms underlying this discrepancy remain unclear, but the lack of a significant difference in the annual eGFR decline in the GLP1Ra-preceding group may be due to the initial dip that occurs in the early phase of SGLT2i treatment

Over time, many people experience loose or sagging skin

Safety considerations: GLP-1 receptor agonists are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Said to enhance fat loss by prioritizing adipose cell fat burning for energy, helping break weight loss plateaus

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January 2013;61(1 Suppl 1):A7, e1476