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Methylcobalamin acts as an essential cofactor in two primary enzyme reactions crucial for human metabolism: Homocysteine to Methionine Conversion: Methylcobalamin is required by the enzyme methionine synthase

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To determine the accurate concentrations of [ 15 N 13 ]-CNCbl used for each extraction, a calibrator solution comprising unlabeled CNCbl (50-100 ng/mL) and labeled [ 15 N 13 ]-CNCbl (50-100 ng/mL) was routinely prepared and measured by LC-MS/MS

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October 10, 2024