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Among the 12% of adults who have ever taken GLP-1 drugs, most report taking them, at least in part, to treat a chronic condition like diabetes or heart disease, with fewer saying they took them only to lose weight
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Our results are consistent with a post hoc analysis of the EXCEL trial [29] which concluded that exenatide combined with SGLT-2i reduced the risk of MACE (defined as cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) compared with exenatide monotherapy and also improved eGFR significantly
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Supplementary Table 2 showed the results of subgroup analysis stratified by SGLT2 inhibitors, with acute heart failure as the outcome
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