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Atherosclerosis is further promoted via immunology and inflammatory mechanisms

Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARgamma and histone acetylation

In addition, serum toxic advanced glycation end-products (TAGE), biomarkers of vascular wall damage, were markedly reduced across all participants

Research indicates that IGF-1 inhibits inflammation and accelerates angiogenesis through Ras/PI3K/IKK/NF-B signaling pathways, creating an optimal environment for tissue repair

In this review, we first examined the background of BDNF, then focused on its neuro-protective mechanisms against ischemic stress, and discussed the potential application of BDNF in clinic Nerve growth factor (NGF), BDNF, neurotrophins (NT) (NT-3, NT-4, NT 4/5 and NT-6) constitute the protein family of mammalian NT (2,3)