These metabolic disturbances arise from disorders in iron absorption, transport, storage, and utilization, influenced by various external factors, diet, intestinal function, genetic predispositions, abnormalities in key proteins, changes in iron storage forms, and iron utilization disorders, all of which interact to contribute to PF ( 2+ , facilitates hydroxyl radical production via the Fenton reaction, exacerbating ROS-induced tissue damage, inflammation, and lipid peroxidation, thereby promoting fibrosis and lung function decline (Sun Y
All 3 forms of SOD (CuZn-SOD, Mn-SOD, and EC-SOD) are widely expressed in the human lung [46, 47]
Curr Med Sci 40:391400
DOPAL can covalently conjugate with lysine residues to form SB adducts
Glutathione deficiency is associated with impaired survival in HIV disease Hong, K.S., et al
The peptide also increases elastin production, which can improve the texture and pliability of stretch marked areas