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[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Dringen R., Brandmann M., Hohnholt M.C., Blumrich E.M

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The hallmark features of the subtype include higher expression of Ki67 (hence higher proliferation rate), lower expression of PR, and in some cases, positive status of HER2 and ER, a more aggressive phenotype with higher chances of early relapse, poor prognosis, lower survival rate, lymph node involvement, and metastasis (99)

87 Therefore, we suggest a triad of elements for further research that could prove useful in the fight against neurological PACS