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In this setting, any perturbation that lowers intracellular GSH to an as yet unknown threshold could eventually induce cell death and, in all likelihood, ferroptosis, but also significantly increase expression and secretion of numerous T2-associated proteins

Interactions Between Peptides and Acids. 2023

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System Xc transports cystine (an alternative precursor of GSH) into cells and exports an equivalent number of glutamate out of the cells through solute carrier family 3 member 2 and solute carrier family 7 member 11 (SLC7A11) transporters (Lu et al., 2024

Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome

Lapenna D, Pierdomenico SD, Ciofani G, et al