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The enhanced accumulation and prolonged retention observed in vivo further confirm the strong brain-penetrating capability of the nanoliposomes 13,58

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Aged garlic extract enhances heme oxygenase-1 and glutamate-cysteine ligase modifier subunit expression via the nuclear factor erythroid 2-related factor 2-antioxidant response element signaling pathway in human endothelial cells

Constipation, deficit in colon contractions and alpha-synuclein inclusions within the colon precede motor abnormalities and neurodegeneration in the central nervous system in a mouse model of alpha-synucleinopathy

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Further co-transfection of His-DDB1, DDA1, GST-tagged COP1, TSF-tagged DET1 and either MBP-Ube2e1-3 or Ube2d3 demonstrated that when TSF-DET1 successfully pulled down MBP-Ube2e2 family members, COP1 was also detected (Fig