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IGF-1 is a small polypeptide consisting of 70 amino acids that is synthesized and secreted into the bloodstream mainly by the liver and some IGF-1 is acted upon by the kidneys or skeletal muscles in an autocrine or paracrine manner in their own tissues or periphery (7)

Synergy was assessed using SynergyFinder 3.0 (35), which computes synergy scores based on different mathematical models

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Here are a few things to keep in mind: CaV channels regulate calcium influx, which is the signal that triggers each heartbeat

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