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never freeze If traveling, tirzepatide can be stored at room temperature (up to 86F / 30C) for up to 21 days Do not use a pen that has been dropped or struck against a hard surface Disposal: Place used pens and syringes in an FDA-approved sharps container never in household trash Side effects and safety considerations Generally, tirzepatide has mild side effects that are typically seen when you start the medication or increase the dose