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50 Mechanically, adropin has been confirmed to regulate mitochondrial energy metabolism through GPR19-p44/42-PDK4 pathway, 51 activate cardiac insulin signaling and improve cardiac efficiency, 52 enhance cardiac glucose oxidation under high fat diet conditions 53 and improve diastolic function by alleviating myocardial fibrosis in diabetic cardiomyopathy rats

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[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Li G., Kawasumi K., Okada Y., Ishikawa S., Yamamoto I., Arai T., Mori N