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Firstly, at the molecular expression level, TMAO can significantly up-regulate the expression of MHC-II molecules and co-stimulatory molecules CD86 on the surface of DCs

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In advanced cancer, the high expression of GPX3 clears excess ROS in the extracellular environment, maintaining the redox homeostasis in the TME, protecting tumor cells and enhancing drug resistance (88)

When the gut lining becomes compromised, it can lead to a wide range of issues including inflammation, poor digestion, and systemic health disruptions

investigated the effect of epithalamin on the pineal and serum melatonin levels in elderly rats