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These fragmented mitochondria increase cellular sensitivity to apoptotic stimuli, while enhanced mitochondrial fusion significantly reduces the occurrence of MOMP, thereby inhibiting cell apoptosis [108]

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In other tissues, BPA is reported to increase expression of the estrogen-responsive genes cyp19a1b ( Aromatase B , neural aromatase), esr1 ( ER ), and esr2 ( ER ) and decrease expression of thyroid receptors TRa ( thraa, thrab ) and TRb ( thrb )