However, despite these benefits, the viscous texture of ophthalmic ointments can cause blurred vision, irritation, and discomfort, which may affect patient compliance, particularly with frequent use [358]
Scientific Reports 7
Potential long-term complications for the patients include duodenal ulcers, intestinal metaplasia with dysplasia, gastric adenocarcinoma (non-cardia intestinal-type), and spontaneous diffuse gastric cancer (29)
Lapointe M
Studies examining multi-dose vial sterility have documented that preservative-containing diluents maintain vial integrity through the labeled use period (PMID: 6562087)
identified and verified ferroptosis-related genes (ATF3, IL-6, IL-1B and EGR1) in the synovial tissue of OA, which were possibly associated with synovial hyperplasia [135]