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KPV has genuine but narrow evidence: it reduced colitis severity in mice through a PepT1-transporter, NF-Binhibiting mechanism, confirmed by more than one group

423 Furthermore, the study emphasized that neurons in specific brain regions, such as the hindbrain and hypothalamus, co-express GLP-1R along with 1-adrenergic and -opioid receptors, suggesting a localized mechanism within the CNS that could coordinate peripheral anti-inflammatory responses

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SFN, Sulforaphane

Kowalczyk P, Sulejczak D, Kleczkowska P et al (2021) Mitochondrial oxidative stressA causative factor and therapeutic target in many diseases