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Mills, D

Mol Psychiatry 30(2):629650 Kirsten K, Pompermaier A, Koakoski G, Mendonca-Soares S, da Costa RA, Maffi VC, Kreutz LC, Barcellos LJG (2021) Acute and chronic stress differently alter the expression of cytokine and neuronal markers genes in zebrafish brain

Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue

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Catechins have the ability to scavenge ROS directly or indirectly via chelation of redox-active metal ions, inactivate enzymes exhibiting prooxidant activity (iNOS), increase the activity of antioxidant enzymes (GPX, catalase, SOD), and inactivate transcription factors involving NF-B (Babu and Liu 2008)

In other words, ISRIB rescues translation only if eIF2 phosphorylation is below the threshold and reduces tumor size in transgenic mice and in patient-derived xenografts without provoking type 1 diabetes (Rabouw et al