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No significant effects on androgen or estrogen receptor systems have been reported, which is relevant context for distinguishing BPC-157 from anabolic compounds that do carry such risks

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[197] demonstrated that polystyrene NPs functionalized by amine groups (PS-NH2) efficiently interact with cell membranes compared to PS-COOH (negatively charged particles)

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The Journal of Clinical Endocrinology & Metabolism, 91 (3), 799-805.