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However, as a macromolecular polysaccharide, the bioavailability of APS is extremely low, the oral absorption efficiency and its specific form in vivo are still unclear, and the current mechanism is not deep enough, lack of loss-of-function validation, and its purity and homogeneity also pose a challenge to the assessment of pharmacological effects

Bonomi M,Holst J,Schlessinger A

A comprehensive understanding of the role of neurotransmitters and the impact of drugs targeting these pathways can pave the way for novel treatment approaches and more suitable therapeutic options

[PubMed: 30293771] 52

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Vitamin B12 is required for concentration and cognitive procedures, such as learning, so a vitamin B12 deficiency can cause trouble focusing and an increased danger for attention disorders