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Therefore, considering significance of both NO-system and egr-1 gene-systems for inflammatory bowel disease (54) as well as for multiple sclerosis (55-57), these may be important also when confronted with severe complications of advanced and poorly controlled IBD as well as multiple sclerosis

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However, elevated MMA and homocysteine concentrations may persist in patients with cobalamin concentrations between 200 and 350 pg/mL

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