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Moreover, oxidation of AAT may lead to a loss of its anti-protease activity that is already lower in AATD, so the antioxidant potential in the treatment of emphysema patients with AATD needs to be considered

The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats PMID: 11735244 Growth Horm IGF Res

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Higher doses and longer use increase the risk