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Symptoms include scratchy burning or stinging in the eyes, red eyes, sensitivity to light, and blurry vision

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NEJM 2025 (REDEFINE-2) Novo Nordisk FDA NDA submission announcement (December 18, 2025) Eli Lilly TRIUMPH-4 topline results (December 2025) Frequently Asked Questions Retatrutide produces higher weight loss at 28.7% versus CagriSema's 20.4%a difference of 21 pounds for a 250-pound person

However, individual variation exists, and certain patient groupsparticularly older adults, those with pre-existing sarcopenia, or individuals with very low baseline muscle massmay require enhanced monitoring and intervention strategies to optimise body composition outcomes during treatment

In our study, mutant mice displayed small but otherwise normal external genitalia