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Prevention: After drawing, hold the syringe needle-up

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Participants who maintained weekly injection schedules experienced sustained reductions in hunger signals and achieved weight losses ranging from 16% to 22%, depending on their dose level

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Off / washout (after the block): A typical research framing runs a defined block (commonly 812 weeks) followed by an off period before any subsequent block, rather than indefinite continuous use because long-term human data simply do not exist