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however, this analysis was conducted in general obesity and diabetes populations, not IBD-specific cohorts, and its findings may not directly translate to patients with underlying intestinal inflammation (97)

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Do patients need lifelong B12 injections?

Serious adverse events (pancreatitis, gallbladder issues, hypoglycemia in diabetic patients) are documented in trials and apply to both forms

5,576,290, 5,674,839, 5,714,576 and 6,051 ,555

What they did not do is test systemically injected IGF-1 LR3 in humans, and the leap from local transgene in a mouse to injected analog in a person is scientifically enormous and unsupported