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Stabilizing the glutathione cycle can disrupt the feed-forward loop linking oxidative stress, mitochondrial dysfunction, vascular impairment, and cardiometabolic disease

Int J Mol Sci 2014;15:21179-21201

10.1002/anie.201107724 37 FarzaeiM

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Night-shift workers present a higher incidence of hormone-dependent cancer which has been related to light-induced melatonin suppression which consequently increases estrogen production

On the other hand, mice with 75% narrowing of the arteries had a 30% decrease in CBF and showed significant spatial memory deficits