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This recent preclinical study showed that the metabolism of racemic ketamine to (2 R ,6 R )-HNK is necessary for the antidepressant effects of ketamine, and that this metabolite itself shows antidepressant-like effects in mice that seem to be independent of the NMDAR

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Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences

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doi: 10.1016/j.lpm.2017.10.006 78 SunXOuZXieMKangRFanYNiuXet al

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For this reason, detox protocols should never be applied uniformly

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