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The observed effects in test models are thought to be associated with changes in growth hormone and IGF-1 levels
When the production of ROS and RNS exceeds the antioxidant defenses, oxidative stress occurs, leading to damage to cellular components including lipids, proteins and deoxyribonucleic acid (DNA)
In fact, the only mutational change so far reported involving a SSTR is the germline R240W mutation in the SSTR5 gene, that was found in one acromegalic patient resistant to octreotide (41)
If you have underlying health conditions or take medication, you should have a thorough evaluation before beginning treatment
Very high is 300 mg or more
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